ABSTRACT

Brain anatomical changes, muscular activity as well as changes in learning and memory function that could arise in these flies from use of the herbas an anti-epileptic molecule during acute and chronic control of seizures were the objectives of our study. This indicates that the extract has neuroprotective compoundsthat ameriolated the neuropathological features in the transgenic flies overexpressing the paralytic gene. There was only relief of symptoms in acute exposure treatments unlike in chronic exposure treatments where the extract and sodium valproate cured the  brain  cellular  biological  defects  leading  to  associated  improvement  in  cognitive  and electrophysiological properties.

Keywords: Imperata cylindrical, myelin, nissl substance, transgenic flies, paralytic gene